Sevda Gholizadeh Shamasbi; Parvin Dehghan; Sakineh Mohammad-Alizadeh Charandabi; Akbar Aliasgarzadeh; Mojgan Mirghafourvand
Volume 20, Issue 11 , 2018, Pages 1-9
Abstract
Background: Polycystic Ovary Syndrome (PCOS) increases the risk of cardiovascular diseases and diabetes, and obesity can acceler- ate this trend. Objectives: This study aimed at determining the effect of prebiotics on anthropometric indices in patients with this syndrome. Methods: This controlled clinical ...
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Background: Polycystic Ovary Syndrome (PCOS) increases the risk of cardiovascular diseases and diabetes, and obesity can acceler- ate this trend. Objectives: This study aimed at determining the effect of prebiotics on anthropometric indices in patients with this syndrome. Methods: This controlled clinical trial was conducted with 62 women from 18- to 45-year-old in the city of Tabriz, Iran, during years 2016 to 2017. Participants were assigned to prebiotic and control groups, using the random blocks method. The intervention group had a daily intake of 20 g of resistant Dextrin, dissolved in a glass of water for three months, and the placebo group had a daily intake of 20 g of Maltodextrin, dissolved in a glass of water for three months. Participants’ Body Mass Index (BMI), weight, waist circumference, and hip circumference were measured before, and three and six months after the intervention. Results: There was no significant difference between the groups in terms of baseline values (P > 0.05). Three months after the intervention, mean (SD) waist circumference, hip circumference, weight, and BMI was 78.11 (9.7), 100.85 (7.7), 65.31 (10.9), and 24.41 (4.2) in the prebiotic group and 86.54 (12.3), 108.72 (10.7), 73.25 (14.7), and 27.73 (5.7) in the control group, respectively. Six months afterthe intervention, mean (SD) anthropometric indices was 78.11 (7.9), 101.45 (7.2), 65.70 (10.3), and 24.54 (3.9) in the prebiotic group and 86.4 (12.6), 108.54 (10.8), 73.8 (14.7), and 27.65 (5.5) in the control group, respectively. According to the Analysis of Variance (ANOVA) test, and with controlled baseline values, all anthropometric indices were significantly lower in the prebiotic group compared to the control group at three (P < 0.001) and six months (P < 0.001).Conclusions: This study confirmed the positive and significant effects of prebiotics in reducing anthropometric indices, three and six months after the intervention in women with PCOS.
Farnaz Faroughi; Sakineh Mohammad-Alizadeh Charandabi; Yousef Javadzadeh; Mojgan Mirghafourvand
Volume 20, Issue 7 , 2018, Pages 1-9
Abstract
Background: Women with borderline gestational diabetes mellitus (BGDM) have a higher risk of complications in comparison with normal women. Objectives: The aim of this study was to determine the effects of garlic pill on fasting blood sugar (FBS) and relapse of prediabetes symptoms (primary outcomes), ...
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Background: Women with borderline gestational diabetes mellitus (BGDM) have a higher risk of complications in comparison with normal women. Objectives: The aim of this study was to determine the effects of garlic pill on fasting blood sugar (FBS) and relapse of prediabetes symptoms (primary outcomes), as well as blood pressure, neonatal anthropometric indices, and mode of delivery (secondary out- comes) in prediabetic pregnant women.Methods: This triple-blind, randomized clinical trial was conducted on 49 women with prediabetes at 24 to 28 weeks of gestation in Tabriz, Iran, during 2015 - 16. The participants were assigned to the intervention (n, 26) and control (n, 23) groups using block randomization. The intervention group received a 400-mg garlic pill per day, while the control group received a placebo pill per day for eight weeks. Four and eight weeks following the intervention, FBS and blood pressure were measured. The newborns’ an- thropometric indices and mode of delivery were also recorded after delivery.Results: The mean FBS level in the garlic group decreased from 106.6 (11.1) mg/dL before the intervention to 83.6 (6.3) mg/dL at four weeks after the intervention and 79.4 (6.1) mg/dL at eight weeks after the intervention (adjusted mean difference, -3.7). The garlic pill also led to a significant decrease in prediabetes symptoms at four weeks after the intervention (P < 0.001) and diastolic blood pressure at four and eight weeks after the intervention (P = 0.041), compared to the control group. No significant difference was observed between the groups in terms of systolic blood pressure at four and eight weeks after the intervention, anthropometric indices, or mode of delivery.Conclusions: The results revealed that garlic pill could reduce FBS level, prediabetes symptoms, and diastolic blood pressure. How- ever, further research with a larger sample size is required for more accurate results.
Somayeh Jamalivand; Sakineh Mohammad-Alizadeh Charandabi; Mojgan Mirghafourvand
Volume 19, Issue 4 , April 2017, , Pages 1-9
Abstract
Background: The use of a training booklet and electronic software has a special place due to lack of time and space constraints.Objectives: This study aimed to compare the effect of electronic software and training booklet on maternal self-esteem and awareness regarding newborn care in nulliparous women.Methods: ...
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Background: The use of a training booklet and electronic software has a special place due to lack of time and space constraints.Objectives: This study aimed to compare the effect of electronic software and training booklet on maternal self-esteem and awareness regarding newborn care in nulliparous women.Methods: This randomized controlled clinical trial was conducted on 126 pregnant women with a gestational age of 36 - 38 weeks in health care centers in the city of Miandoab, Iran from February 2015 until April 2016. Using a randomized block design, participants were assigned into 2 groups (42 mothers receiving electronic software and 42 mothers receiving training booklet) and control group (42 mothers receiving postpartum routine training). An oral training session was held for participants in both intervention groups. Then, a training booklet or electronic software was provided to them. Maternal self-esteem and awareness regarding newborn care questionnaires were completed by participants in the 3 groups at the start of the intervention and 4 weeks after the childbirth.Results: After controlling the baseline values, the mean score of self-confidence in the training booklet group (adjusted mean difference = 5.6; 95% confidence interval = 1.2 to 10.0; P = 0.012) was significantly higher compared with the control group. Furthermore, the mean score of awareness regarding newborn care in the training booklet group (1.5; 0.6 to 2.3; P < 0.001) and the electronic software group (2.0; 1.2 to 2.9; P < 0.001) was significantly higher compared with the control group. There was no statistically significant difference between the 2 groups after the intervention in terms of level of awareness and self-confidence.Conclusions: The results showed a significant effect of electronic software and training booklet in raising awareness about newborn care and self-confidence. Therefore, these methods are advisable to mothers.
Havin Zandinava; Fahimeh Sehhatti Shafaei; Sakineh Mohammad-Alizadeh Charandabi; Ghanbari Homayi; Mojgan Mirghafourvand
Volume 19, Issue 4 , April 2017, , Pages 1-9
Abstract
Background: Gestational diabetes is a particular disorder during pregnancy which can cause complications for mother and fetus. One reason for the limited success in the treatment of diabetes is the lack of patient participation in the process of treatment. Selfcare education is an important principle ...
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Background: Gestational diabetes is a particular disorder during pregnancy which can cause complications for mother and fetus. One reason for the limited success in the treatment of diabetes is the lack of patient participation in the process of treatment. Selfcare education is an important principle in the treatment of diabetes that can enhance the quality of life.Objectives: This study aimed to determine the effect of educational package on self-care behavior, quality of life, FBS (Fasting Blood Sugar), and GTT (Glucose Tolerance Test) among women with gestational diabetes.Methods: This randomized controlled clinical trial was performed on 92 pregnant women with gestational diabetes (n = 46 in each group) referring to diabetes clinic of Tohid hospital in Sanandaj, Iran. The educational program was designed in four sessions (one session per week) for the intervention group and included routine prenatal care along with education on self-care through lecture and question and answer. The participants also received educational booklet at the end of the first session. The control group received only routine prenatal care. Before and four weeks after the intervention, self-care and quality of life questionnaires were completed by the participants in both groups, and fasting blood glucose and GTT were measured.Results: After adjusting for the baseline score, the mean score of self-care behaviors was significantly higher in the intervention group than the control group four weeks after the intervention [adjusted mean difference: 19.5; 95% confidence interval: 14.4 to 24.6; P < 0.001]. Also, by adjusting for the baseline values, there was a statistically significant difference in the mean level of blood glucose at the time points of one hour after GTT [-21.6; -32.1 TO -11.1; P < 0.001] and two hours after GTT [-17.3; -23.0 to -11.6; P < 0.001]. No statistically significant difference was seen in the FBS (P = 0.443) and quality of life (P = 0.264) four weeks after the intervention.Conclusions: Self-care education can improve self-care behavior in women with gestational diabetes and it is also effective in impaired glucose tolerance.
